Sept. 18 Tampa Bay (0–2) at Atlanta (1–1)
Atlanta is coming off a bad loss against the Cincinnati Bengals and are at home looking to get back in the win column. The Tampa Bay Buccaneers suffered a heartbreaking loss to the lowly St. Louis Rams and are searching for answers. The Falcons are difficult to beat at home and the Bucs are reeling.
Take: Atlanta

Sept. 21 San Diego (1–1) at Buffalo (2–0)
Tight end Antonio Gates led the charge for San Diego with three touchdowns as they upset the Seattle Seahawks last week. Quarterback Phillip Rivers looked exceptional, but the Buffalo Bills are turning some heads this season. Their defence has been rock solid and will be tough to beat at home.
Take: Buffalo

Sept. 21 Tennessee (1–1) at Cincinnati (2–0)
An injury to star receiver AJ Green could be detrimental moving forward, but the Bengals still have a great defence. The Tennessee Titans looked average in a blowout loss to Dallas and young quarterback Jake Locker could be in for a long day against the Cincy secondary.
Take: Cincinnati

Sept. 21 Baltimore (1–1) at Cleveland (1–1)
Amidst the off field turmoil, the Ravens pulled out a huge win over the Pittsburgh Steelers. Now they travel to Cleveland to take on the upstart Browns who stunned everyone by beating the New Orleans Saints. The Browns defence is very underrated and they could be a legitimate threat in the American Football Conference.
Take: Cleveland

Sept. 21 Green Bay (1–1) at Detroit (1–1)
The Packers trailed the New York Jets 21–3 at one point, but a huge day from receiver Jordy Nelson brought them back to win. The Detroit Lions offence sputtered against the tough Carolina Panthers defence last week, but the Packers defence looked very pedestrian against a sub-par Jets team.
Take: Detroit

Sept. 21 Indianapolis (0–2) at Jacksonville (0–2)
It’s only week three but the Jacksonville Jaguars are already in midseason form. They were abused 41–7 by Washington Redskins backup quarterback Kirk Cousins. The Colts let one slip away on Monday night, but if they don’t manage to beat the Jags, hell will freeze over.
Take: Indianapolis

Sept. 21 Oakland (0–2) at New England (1–1)
The Patriots looked like their old selves in week two with dismantling the Minnesota Vikings. At home against the equally weak Oakland Raiders, quarterback Tom Brady and company should roll in this one.
Take: New England

Sept. 21 Minnesota (1–1) at New Orleans (0–2)
Nobody predicted the Saints would be 0–2 to start the year. Quarterback Drew Brees and their powerful offence went 8–0 at home last year and unfortunately for Minnesota, this is the Saints home opener.
Take: New Orleans

Sept. 21 Houston (1–1) at New York Giants (0–2)
After a string of 15 straight losses, the Texans actually looked good in a game. They now get the abysmal New York Giants, who can’t score or stop giving up points. Houston’s defence should make it a long day for quarterback Eli Manning.
Take: Houston

Sept. 21 Washington (1–1) at Philadelphia (2–0)
The Washington Redskins blew out the Jaguars, but they have a tough matchup now with the Philadelphia Eagles. The Eagles mounted a late surge to win last week. This will be a tough divisional matchup, but being at home they should have the upper hand against the Skins.
Take: Philadelphia

Sept. 21 Dallas (1–1) at St. Louis (1–1)
Kicker Greg Zuerlein connected on four field goals, including the game winner as time expired to give the Rams a surprising win in week two. The Cowboys used a dominant performance by Demarco Murray, but the Rams defence won’t let that happen again. Quarterback Tony Romo will be relied to win the game.
Take: Dallas

Sept. 21 San Francisco (1–1) at Arizona (2–0)
San Francisco choked away a 17-point lead on Sunday Night Football for their first loss of the season. Quarterback Colin Kaepernick looked terrible and he could be in tough against a top notch Arizona defence.
Take: Arizona

Sept. 21 Kansas City (0–2) at Miami (1–1)
With the potential for Jamaal Charles’ ankle injury to be serious, the Chiefs offence could be in big trouble. Kansas City just isn’t the same team they were last year. Miami was beaten badly last week, but remain a solid team at home.
Take: Miami
Sept. 21 Denver (2–0) at Seattle (1–1)
The game of the week features a Super Bowl rematch between Peyton Manning’s Broncos and Richard Sherman’s Seahawks. Seattle is reeling after a bad loss to the Chargers and the Broncos are rolling after two big wins. Logic would take the home team, but it doesn’t stand up this time.
Take: Denver

Sept. 21 Pittsburgh (1–1) at Carolina (2–0)
The Steelers were simply terrible on Thursday Night Football and now have to face the ferocious Panthers defence on their own turf. Quarterback Ben Roethlisberger is getting old and he could be in for a long game.
Take: Carolina

Sept. 22 Chicago (1–1) at New York Jets (1–1)
Monday Night Football in week three sees the Bears take on the Jets. Chicago mounted a huge second half comeback to stun the 49ers, whereas the Jets gave up a big comeback to lose to the Packers. The Bears have a good matchup with their talented receivers taking on the weak Jets secondary.
Take: Chicago